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If a cation having a plus 3 charge is used, then three times as much anion having a minus 1 charge is needed, and so on.
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Some specific examples of phatmaceutical actives that can be used in the disclosed ionic liquids include, but are not limited to, aspirin, LH3RlUMTM, isoniazid, penicillin, PRONTOSILTm, cisplatin, 6-mercaptopurine, RITUXANTM, TAXOLTM, phenobarbital, PROZACTM, ALLEGR.
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Naproxen information Naproxen is an anti-inflammatory non-steroidal anti-inflammatory (NSAID) medicine.
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La Sociedad Americana de Depresin y Estrs Anxiety and Depression Association of America ofrece informacin detallada sobre y mejorar la aptitud mental de todo el mundo.
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Indication: For the treatment and the management of acid-reflux disorders (GERD), peptic ulcer disease, heartburn, and acid indigestion.
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Additional functionality can be obtained by using the disclosed ionic liquid compositions as solvents to dissolve a solute(s) with another desired property, thus resulting in a solution where the ions of the ionic liquid as well as the solute contribute desired properties to the composition.
Per cinque anni mi è stato somministrato lo Xanax - oltre a vari antidepressivi che non hanno fatto altro che farmi stare peggio, poichè i benefici erano solo iniziali ma si sa, ci si abitua facilmente a queste porcherie pertanto vi è sempre il bisogno di alzare la dose.
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Pero controlar de forma cuidadosa la cantidad de aire que el respirador artificial enva a los pulmones y mantener la presin dentro de los pulmones durante procedimientos como la prueba de apnea, para comprobar la respiracin, mejora la viabilidad del pulmn de manera considerable, de acuerdo con el estudio.
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In another embodiment, effective of CNS active agent in the kit may be at least two times lower than the same CNS active agent when used as a stand alone medication.
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The amount of antidepressant in compositions of the invention will vary according to the type and identity of the antidepressant, the concentration and identity of the NMDA-receptor antagonist, and the painful indiction treated.
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Formulation and dosage of the pharmaceutical composition will now be described, with reference to a time-release component that makes possible overlapping effectiveness of the CNS active agent and the neuromodulators as are discussed above.
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The reaction proceeds via ion exchange reaction in solvent system media (solvent system is the solvent or the mixture of the solvents in which at least one of the starting materials dissolves).
Hydrochlorothiazide is a "water pill" (diuretic) and causes your body to get rid of extra salt and water.
For example, the starting materials and reagents used in preparing the disclosed compounds and compositions are either available from commercial suppliers such as Aldrich Chemical Co.
It is understood that where reduce or prevent are used, unless specifically indicated otherwise, the use of the other word is also expressly disclosed.
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In another embodiment (a) CNS active agent(s) are selected from the following groups: benzodiazepines, atypical neuroleptics, barbiturates, sodium oxybate, opiates, or combinations thereof; (b) hypertensive agent is a selective alpha ADR receptor agonist Phenylephrine (vagal afferent neuromodulator); (c) and instructions for delay of about 15-30 minutes between administration of (a) and (b).
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The study was published May 4 in the journal Science Translational Medicine.
Olanzapine can cause high blood sugar (hyperglycemia).
As described herein, nanoerythrosomes are delivery devices that can be used to deliver the compositions disclosed herein.
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The compounds disclosed herein may also be combined or used in combination with other agents useful in the treatment of dopamine receptor-mediated disorders.
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Question (5) Following treatment, did you feel anxious?
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The term “nonrelease controlling excipient” refers to an excipient whose primary function do not include modifying the duration or place of release of the active substance from a dosage form as compared with a conventional immediate release dosage form.
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Some classes of CNS active agents that require increasing doses include pain reducing drugs, selective serotonin re-uptake inhibitors, antidepressants, anti-convulsants, hypnotics, anesthetics, sedative agents, angiolytics, NSAIDs, xanthines, antipsychotics, appetite suppressants, sleep agents, antibiotics, antivirals, insulin resistance drugs, antihypertensives, and anti-asthma drugs.
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Many of the disclosed ionic liquid compositions can be used therapeutically as neat ionic liquids.
Certain physical exam findings, such as hyperactive deep tendon reflexes, suggest that the weakness is due to disease in the spinal cord or brain.
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As used herein, the terms below have the meanings indicated.
CNS active agents of the present invention also include “serotonin- and noradrenalin-reuptake inhibitors” (SNRIs).
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Different individuals may respond to medication in different ways.
For example, a glass ionic liquid composition can be cooled to form a pill.
Findings presented at meetings are typically viewed as preliminary until theyve been published in a peerreviewed journal.
The method as recited claim 16, wherein said compound is characterized by decreased inhibition of at least one cytochrome P 450 or monoamine oxidase isoform in said subject per dosage unit thereof as compared to the non-isotopically enriched compound.
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Each study had a number of arms: (1) drug alone, (2) drug with NM1 (PSE), (3) drug with NM2 (GUA), (4) drug with both NM's, taken without synchronization, and finally the experimental arm, (5) drug with both NM's synchronized with the t-max of the drug.
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Atorvastatin, sold under the trade name LIPITORTm, and pravastatin, sold under the trade name PRAVACHOLTm, are used to treat cholesterol and are further examples of suitable compounds that can be used to prepare the disclosed ionic liquid compositions.
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In an embodiment of the present invention, preferably, the antidepressant is a norepinephrine-reuptake inhibitor, a tricyclic antidepressant, amitriptyline, or, more preferably, amitriptyline hydrochloride.
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A number of serious medical conditions can present with bedwetting, such as seizures and diabetes, as well as anatomical abnormalities involving the spinal cord.
The deuterium enrichment can be determined using conventional analytical methods known to one of ordinary skill in the art, including mass spectrometry and nuclear magnetic resonance spectroscopy.
The reaction mixture is cooled to room temperature, and then 60 mL of chloroform is added.
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The composition of claim 31, wherein the at least one kind of cation comprises the cation of 2-aminothiazole, 6-azauridine, 6-mercaptopurine, 9-aminocamptothecin, acetarsone, acetazolamide, acetosulfone, acetylcysteine, acetylpheneturide, acranil, acrivastine, adrenalone, albutoin, aldioxa, alibendol, alizapride, alkofanone, allopurinol, ambenonium, ambroxol, ambutonium, amexinium, aminitrozole, amiphenazole, amisulpride, anagrelide, arsanilate, arshpenamine, asoxime, azidamfenicol, benfluorex, benfunolol, benserazide, benzaepril, benzilonium, benznidazole, benzoxonium, benzoylpas, berberine, bibenzonium, brequinar, brodimoprim, bromhexine, bromopride, bromo-salicylchloranilide, bucillamine, buformin, bufuralol, bumadizon, bunitrolol, buthalital, cabergoline, carbachol, carbarsone, carbidopa, cariporide, carnitine, caroxazone, celecoxib, cephaeline, cetalkonium, chloguanide, chloramphenicol, chlordantoin, chlorisonclamine, chloroquine, cholic acid, choline, ciclonicate, cilostazol, cimetidine, cinepazide, cinitapride, cisapride, clanobutin, clometocillin, clomiphene, cloricromen, clortermine, cyamelide, cyclazocine, dapsone, dimefline, diphetarsone, distigmine, dithiazanine, donepezil, dopamine, echothiophate, edrophonium, efavirenz, elfornithine, enfenamic acid, etifoxine, etodroxizine, fampridine, fazadinium, fendiline, fenproporex, finasteride, flufenamic acid, flumethiazide, fluoxetine, flurazepam, flutamide, fomepizole, fominoben, hexafluorenium, hydroxystilbamidine, ibudilast, indalpine, indeloxazine, ipratropium, irsogladine, isobutyl p-aminobenzoate, isoetharine, levosimendan, lisuride, lodoxamide, mesalamine, mesoxalate, metformin, methionine, methoxyphenamine, methyl hexaneamine, methylene blue, methylthiouracil, metrons, metyrosine, minoxidil, nadoxolol, nafronyl, naphazoline, naratriptan, neostigmine, nicametate, niclosamide, nicorandil, nilutamide, niridazole, nitazoxanide, nordefrin, obidoxime, omapatrilat, orotic acid, oxaceprol, oxitropium, ozagrel, pamidronic acid, p-aminobenzoic acid, p-aminopropiophenon, pelletierine, pemoline, penicillamine, pentamethonium, pentamidine, pentoxifylline, pergolid, perhexiline, phenmetrazine, phentolamine, phenylephrine, picotamide, pidotimod, pimobendan, pinacidil, pramipexole, prenylamine, prinomastat, pyridinol carbamate, pyridoxine, pyrimethamine, ramatroban, remoxipride, repinotan, riluzole, ritodrine, succinimide, succinylcholine, sulfamethoxazole, sulfapyridine, sulpiride, synephrine, tamsulosin, tedisamil, tenuazonic acid, terazosin, terbutaline, tetrazepam, tetroxoprim, thiabendazole, thiamine, thiopental, tiapride, timonacid, tiopronin, tiotropium, tizanidine, tolazoline, tropicamide, valnoctamide, zafirlukast, or a cationic derivative thereof.
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